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Spotlight on tocilizumab and its potential in the treatment of systemic sclerosis

Systemic sclerosis (SSc) is a multisystem disease characterized by extensive collagen deposition in skin and internal organs, fibrointimal microvasculopathy, and activation of the immune system. T cells and B cells can promote fibrosis in SSc. Interleukin (IL)-6 is implicated in the pathogenesis of...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Autor principal: Sakkas, Lazaros I
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010079/
https://ncbi.nlm.nih.gov/pubmed/27621593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S99696
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