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Development of a Method for the N-Arylation of Amino Acid Esters with Aryl Triflates
[Image: see text] A general method for the N-arylation of amino acid esters with aryl triflates is described. Both α- and β-amino acid esters, including methyl, tert-butyl, and benzyl esters, are viable substrates. Reaction optimization was carried out by design of experiment (DOE) analysis using JM...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2016
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010016/ https://ncbi.nlm.nih.gov/pubmed/27498618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b02082 |
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