Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice

A number of studies have shown that CD8+ T cells mediate protective anti-malaria immunity in a mouse model. However, whether human CD8+ T cells play a role in protection against malaria remains unknown. We recently established human immune system (HIS) mice harboring functional human CD8+ T cells (H...

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Publicado no:Vaccine
Main Authors: Li, Xiangming, Huang, Jing, Zhang, Min, Funakoshi, Ryota, Sheetij, Dutta, Spaccapelo, Roberta, Crisanti, Andrea, Nussenzweig, Victor, Nussenzweig, Ruth S., Tsuji, Moriya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009892/
https://ncbi.nlm.nih.gov/pubmed/27502569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.006
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