Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle.

Two point mutations were identified within the gene encoding bovine CD18 in a Holstein calf afflicted with leukocyte adhesion deficiency (LAD). One mutation causes an aspartic acid to glycine substitution at amino acid 128 (D128G) in the highly conserved extracellular region of this adhesion glycopr...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Shuster, D E, Kehrli, M E, Ackermann, M R, Gilbert, R O
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1384046/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9225
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