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Deletion of interleukin-6 in monocytes/macrophages suppresses the initiation of hepatocellular carcinoma in mice

BACKGROUND: Hepatocellular carcinoma (HCC) is associated with inflammation, and roughly 30 % of the global population shows serological evidence of current or past infection with hepatitis B or hepatitis C virus. Resident hepatic macrophages, known as Kupffer cells (KCs), are considered as the speci...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Kong, Lingxiang, Zhou, Yongjie, Bu, Hong, Lv, Tao, Shi, Yujun, Yang, Jiayin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009700/
https://ncbi.nlm.nih.gov/pubmed/27589954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0412-1
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