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Investigating cellular network heterogeneity and modularity in cancer: a network entropy and unbalanced motif approach

BACKGROUND: Cancer is increasingly recognized as a cellular system phenomenon that is attributed to the accumulation of genetic or epigenetic alterations leading to the perturbation of the molecular network architecture. Elucidation of network properties that can characterize tumor initiation and pr...

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Pubblicato in:BMC Syst Biol
Autori principali: Cheng, Feixiong, Liu, Chuang, Shen, Bairong, Zhao, Zhongming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009528/
https://ncbi.nlm.nih.gov/pubmed/27585651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0309-9
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