Adenosine monophosphate deaminase 3 activation shortens erythrocyte half-life and provides malaria resistance in mice

The factors that determine red blood cell (RBC) lifespan and the rate of RBC aging have not been fully elucidated. In several genetic conditions, including sickle cell disease, thalassemia, and G6PD deficiency, erythrocyte lifespan is significantly shortened. Many of these diseases are also associat...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hortle, Elinor, Nijagal, Brunda, Bauer, Denis C., Jensen, Lora M., Ahn, Seong Beom, Cockburn, Ian A., Lampkin, Shelley, Tull, Dedreia, McConville, Malcolm J., McMorran, Brendan J., Foote, Simon J., Burgio, Gaetan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009516/
https://ncbi.nlm.nih.gov/pubmed/27465915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-666834
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