Carfilzomib significantly improves the progression-free survival of high-risk patients in multiple myeloma

The presence of certain high-risk cytogenetic abnormalities, such as translocations (4;14) and (14;16) and deletion (17p), are known to have a negative impact on survival in multiple myeloma (MM). The phase 3 study ASPIRE (N = 792) demonstrated that progression-free survival (PFS) was significantly...

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Bibliographic Details
Published in:Blood
Main Authors: Avet-Loiseau, Hervé, Fonseca, Rafael, Siegel, David, Dimopoulos, Meletios A., Špička, Ivan, Masszi, Tamás, Hájek, Roman, Rosiñol, Laura, Goranova-Marinova, Vesselina, Mihaylov, Georgi, Maisnar, Vladimír, Mateos, Maria-Victoria, Wang, Michael, Niesvizky, Ruben, Oriol, Albert, Jakubowiak, Andrzej, Minarik, Jiri, Palumbo, Antonio, Bensinger, William, Kukreti, Vishal, Ben-Yehuda, Dina, Stewart, A. Keith, Obreja, Mihaela, Moreau, Philippe
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009511/
https://ncbi.nlm.nih.gov/pubmed/27439911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707596
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