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Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation

TGFβ2 (transforming growth factor-β2) is a key growth factor regulating epithelial to mesenchymal transition (EMT). TGFβ2 triggers cardiac progenitor cells to differentiate into mesenchymal cells and give rise to the cellular components of coronary vessels as well as cells of aortic and pulmonary va...

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Detalles Bibliográficos
Publicado en:Toxicol Sci
Main Authors: Huang, Tianfang, Ditzel, Eric J., Perrera, Alec B., Broka, Derrick M., Camenisch, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009438/
https://ncbi.nlm.nih.gov/pubmed/26354774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv191
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