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Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation

TGFβ2 (transforming growth factor-β2) is a key growth factor regulating epithelial to mesenchymal transition (EMT). TGFβ2 triggers cardiac progenitor cells to differentiate into mesenchymal cells and give rise to the cellular components of coronary vessels as well as cells of aortic and pulmonary va...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Huang, Tianfang, Ditzel, Eric J., Perrera, Alec B., Broka, Derrick M., Camenisch, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009438/
https://ncbi.nlm.nih.gov/pubmed/26354774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv191
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