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Peptidomimetics Based On Dehydroepiandrosterone Scaffold: Synthesis, Antiproliferation Activity, Structure-Activity Relationship, and Mechanisms

A series of novel peptidomimetics bearing dehydroepiandrosterone moiety were designed, synthesized, and evaluated for their inhibition activities against cell proliferation. According to the preliminary studies on inhibitory activities, some of the newly prepared compounds indicated significantly in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Xiaohui, Su, Haihuan, Wang, Wenda, Chen, Changshui, Cao, Xiufang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009342/
https://ncbi.nlm.nih.gov/pubmed/27585479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32654
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