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Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies

BACKGROUND: The primary biomarkers used to define CKD are serum creatinine and albuminuria. These biomarkers have directed focus on the filtration and barrier functions of the kidney glomerulus even though albuminuria results from tubule dysfunction as well. Given that proximal tubules make up ∼90%...

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Publicat a:Nephrol Dial Transplant
Autors principals: Waikar, Sushrut S., Sabbisetti, Venkata, Ärnlöv, Johan, Carlsson, Axel C., Coresh, Josef, Feldman, Harold I., Foster, Meredith C., Fufaa, Gudeta D., Helmersson-Karlqvist, Johanna, Hsu, Chi-yuan, Kimmel, Paul L., Larsson, Anders, Liu, Yumin, Lind, Lars, Liu, Kathleen D., Mifflin, Theodore E., Nelson, Robert G., Risérus, Ulf, Vasan, Ramachandran S., Xie, Dawei, Zhang, Xiaoming, Bonventre, Joseph V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009290/
https://ncbi.nlm.nih.gov/pubmed/27270293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw203
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