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Enthalpic Breakdown of Water Structure on Protein Active-Site Surfaces

The principles underlying water reorganization around simple non-polar solutes are well understood and provide the framework for classical hydrophobic effect, whereby water molecules structure themselves around solutes so that they maintain favorable energetic contacts with both the solute and with...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Haider, Kamran, Wickstrom, Lauren, Ramsey, Steven, Gilson, Michael K., Kurtzman, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009012/
https://ncbi.nlm.nih.gov/pubmed/27169482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b01094
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