Genetic Risk and Longitudinal Disease Activity in Systemic Lupus Erythematosus Using Targeted Maximum Likelihood Estimation

Systemic lupus erythematous (SLE) is a chronic autoimmune disease associated with genetic and environmental risk factors. However, the extent to which genetic risk is causally associated with disease activity is unknown. We utilized longitudinal targeted maximum likelihood estimation to estimate the...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Gianfrancesco, Milena A., Balzer, Laura, Taylor, Kimberly E., Trupin, Laura, Nititham, Joanne, Seldin, Michael F., Singer, Amanda Wheeler, Criswell, Lindsey A., Barcellos, Lisa F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008986/
https://ncbi.nlm.nih.gov/pubmed/27467283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.33
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