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Mutation of the Regulator of G Protein Signaling Crg1 Increases Virulence in Cryptococcus neoformans

The regulator of G protein signaling homolog Crg1 was found to be a key regulator of pheromone-responsive mating in the opportunistic human fungal pathogen Cryptococcus neoformans. A mutation in the CRG1 gene has greatly increased virulence in the prevalently distributed MATα strains of the fungus....

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Bibliografske podrobnosti
Main Authors: Wang, Ping, Cutler, Jim, King, Jill, Palmer, Daniel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC500888/
https://ncbi.nlm.nih.gov/pubmed/15302835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.4.1028-1035.2004
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