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Mutation of the Regulator of G Protein Signaling Crg1 Increases Virulence in Cryptococcus neoformans
The regulator of G protein signaling homolog Crg1 was found to be a key regulator of pheromone-responsive mating in the opportunistic human fungal pathogen Cryptococcus neoformans. A mutation in the CRG1 gene has greatly increased virulence in the prevalently distributed MATα strains of the fungus....
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC500888/ https://ncbi.nlm.nih.gov/pubmed/15302835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.4.1028-1035.2004 |
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