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Cell-Wide DNA De-Methylation and Re-Methylation of Purkinje Neurons in the Developing Cerebellum

Global DNA de-methylation is thought to occur only during pre-implantation and gametogenesis in mammals. Scalable, cell-wide de-methylation has not been demonstrated beyond totipotent stages. Here, we observed a large scale de-methylation and subsequent re-methylation (CDR) (including 5-methylcytosi...

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Vydáno v:PLoS One
Hlavní autoři: Zhou, Feng C., Resendiz, Marisol, Lo, Chiao-Ling, Chen, Yuanyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008790/
https://ncbi.nlm.nih.gov/pubmed/27583369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162063
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