Regulatory CD4+ T-Cell Subsets and Anti-Citrullinated Protein Antibody Repertoire: Potential Biomarkers for Arthritis Development in Seropositive Arthralgia Patients?

OBJECTIVE: Seropositive arthralgia patients (SAP) are at high risk of developing rheumatoid arthritis (RA). This prospective study aimed to determine whether altered peripheral regulatory T-cells (Tregs) and defined subsets, besides a broadened anti-citrullinated protein antibody (ACPA) response, ma...

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Vydáno v:PLoS One
Hlavní autoři: Janssen, Koen M. J., Westra, Johanna, Chalan, Paulina, Boots, Annemieke M. H., de Smit, Menke J., van Winkelhoff, Arie Jan, Vissink, Arjan, Brouwer, Elisabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008772/
https://ncbi.nlm.nih.gov/pubmed/27585422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162101
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