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Epithelial Tumors Originate in Tumor Hotspots, a Tissue-Intrinsic Microenvironment

Malignant tumors are caused by uncontrolled proliferation of transformed mutant cells that have lost the ability to maintain tissue integrity. Although a number of causative genetic backgrounds for tumor development have been discovered, the initial steps mutant cells take to escape tissue integrity...

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Bibliografische gegevens
Gepubliceerd in:PLoS Biol
Hoofdauteurs: Tamori, Yoichiro, Suzuki, Emiko, Deng, Wu-Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008749/
https://ncbi.nlm.nih.gov/pubmed/27584724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002537
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