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In vitro differentiation of embryonic stem cells into lymphocyte precursors able to generate T and B lymphocytes in vivo.

Embryonic stem cells can be induced in vitro, by coculture with the stromal line RP.0.10 and a mixture of interleukins 3, 6, and 7, to differentiate into T (Joro75+) and B (B-220+) lymphocyte progenitors and other (Thy-1+, PgP-1+, c-kit+, Joro75-, B-220-, F4/80-, Mac-1-) hemopoietic precursors. The...

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Bibliografski detalji
Glavni autori: Gutierrez-Ramos, J C, Palacios, R
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC50087/
https://ncbi.nlm.nih.gov/pubmed/1409620
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