Validation of the 17-item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) data

OBJECTIVE: To define thresholds of clinically significant change in 17-item Hamilton Depression Rating Scale (HDRS-17) scores using the Clinical global Impression-Improvement (CGI-I) scale as a gold standard. METHODS: We conducted a secondary analysis of individual patient data from the Pharmacogeno...

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Veröffentlicht in:Hum Psychopharmacol
Hauptverfasser: Bobo, William V., Angleró, Gabriela C., Jenkins, Gregory, Hall-Flavin, Daniel K., Weinshilboum, Richard, Biernacka, Joanna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008690/
https://ncbi.nlm.nih.gov/pubmed/26999588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hup.2526
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