Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration

Renal ischemia-reperfusion (I/R) in male rats causes reductions in plasma testosterone, and infusion of testosterone 3 h postreperfusion is protective. We tested the hypotheses that acute high doses of testosterone promote renal injury after I/R, and that acute low-dose testosterone is protective by...

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Publicado no:Am J Physiol Renal Physiol
Main Authors: Patil, Chetan N., Wallace, Kedra, LaMarca, Babbette D., Moulana, Mohadetheh, Lopez-Ruiz, Arnaldo, Soljancic, Andrea, Juncos, Luis A., Grande, Joseph P., Reckelhoff, Jane F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008676/
https://ncbi.nlm.nih.gov/pubmed/27252490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00454.2015
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