Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury

Acute kidney injury (AKI) is a common and independent risk factor for death and chronic kidney disease (CKD). Despite promising preclinical data, there is no evidence that antioxidants reduce the severity of injury, increase recovery, or prevent CKD in patients with AKI. Pyridoxamine (PM) is a struc...

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Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Skrypnyk, Nataliya I., Voziyan, Paul, Yang, Haichun, de Caestecker, Christian R., Theberge, Marie-Claude, Drouin, Mathieu, Hudson, Billy, Harris, Raymond C., de Caestecker, Mark P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008672/
https://ncbi.nlm.nih.gov/pubmed/27194713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00056.2016
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