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Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury

Acute kidney injury (AKI) is a common and independent risk factor for death and chronic kidney disease (CKD). Despite promising preclinical data, there is no evidence that antioxidants reduce the severity of injury, increase recovery, or prevent CKD in patients with AKI. Pyridoxamine (PM) is a struc...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Main Authors: Skrypnyk, Nataliya I., Voziyan, Paul, Yang, Haichun, de Caestecker, Christian R., Theberge, Marie-Claude, Drouin, Mathieu, Hudson, Billy, Harris, Raymond C., de Caestecker, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008672/
https://ncbi.nlm.nih.gov/pubmed/27194713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00056.2016
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