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Delivery of interleukin-10 via injectable hydrogels improves renal outcomes and reduces systemic inflammation following ischemic acute kidney injury in mice

Injectable hydrogels can be used to deliver drugs in situ over a sustained period of time. We hypothesized that sustained delivery of interleukin-10 (IL-10) following acute kidney injury (AKI) would mitigate the local and systemic proinflammatory cascade induced by AKI and reduce subsequent fibrosis...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Soranno, Danielle E., Rodell, Christopher B., Altmann, Christopher, Duplantis, Jane, Andres-Hernando, Ana, Burdick, Jason A., Faubel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008670/
https://ncbi.nlm.nih.gov/pubmed/26962109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00579.2015
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