Key roles of necroptotic factors in promoting tumor growth

Necroptotic factors are generally assumed to play a positive role in tumor therapy by eliminating damaged tumor cells. Here we show that, contrary to expectation, necroptotic factors RIPK1, RIPK3, and MLKL promote tumor growth. We demonstrate that genetic knockout of necroptotic genes RIPK1, RIPK3,...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Liu, Xinjian, Zhou, Min, Mei, Ling, Ruan, Jiaying, Hu, Qian, Peng, Jing, Su, Hang, Liao, Hong, Liu, Shanling, Liu, WeiPing, Wang, He, Huang, Qian, Li, Fang, Li, Chuan-Yuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008357/
https://ncbi.nlm.nih.gov/pubmed/26959742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7924
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