Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro

Renal tubulointerstitial fibrosis is the common and final pathologic change of kidney in end-stage renal disease. Interesting, endoplasmic reticulum (ER) stress is known to contribute to the pathophysiological mechanisms during the development of renal fibrosis. Here, we investigated the effects of...

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Publicado en:Oncotarget
Autores principales: Liu, Shing-Hwa, Yang, Ching-Chin, Chan, Ding-Cheng, Wu, Cheng-Tien, Chen, Li-Ping, Huang, Jenq-Wen, Hung, Kuan-Yu, Chiang, Chih-Kang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008348/
https://ncbi.nlm.nih.gov/pubmed/26959118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7904
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