Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression

The spectrum of somatic mutation of the most aggressive forms of neuroblastoma is not completely determined. We sought to identify potential cancer drivers in clinically aggressive neuroblastoma. Whole exome sequencing was conducted on 17 germline and tumor DNA samples from high-risk patients with a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lasorsa, Vito Alessandro, Formicola, Daniela, Pignataro, Piero, Cimmino, Flora, Calabrese, Francesco Maria, Mora, Jaume, Esposito, Maria Rosaria, Pantile, Marcella, Zanon, Carlo, De Mariano, Marilena, Longo, Luca, Hogarty, Michael D., de Torres, Carmen, Tonini, Gian Paolo, Iolascon, Achille, Capasso, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008327/
https://ncbi.nlm.nih.gov/pubmed/27009842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8187
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