Long-term prognostic implications and therapeutic target role of hexokinase II in patients with nasopharyngeal carcinoma

Tumor cells preferentially use anaerobic glycolysis rather than oxidative phosphorylation to generate energy. Hexokinase II (HK-II) is necessary for anaerobic glycolysis and displays aberrant expression in malignant cells. The current study aimed to evaluate the role of HK-II in the survival and bio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Meng-Xia, Hua, Yi-Jun, Wang, Hai-Yun, Zhou, Ling, Mai, Hai-Qiang, Guo, Xiang, Zhao, Chong, Huang, Wen-Lin, Hong, Ming-Huang, Chen, Ming-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008285/
https://ncbi.nlm.nih.gov/pubmed/26848773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7116
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