Cerebellar output controls generalized spike‐and‐wave discharge occurrence

OBJECTIVE: Disrupting thalamocortical activity patterns has proven to be a promising approach to stop generalized spike‐and‐wave discharges (GSWDs) characteristic of absence seizures. Here, we investigated to what extent modulation of neuronal firing in cerebellar nuclei (CN), which are anatomically...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Kros, Lieke, Eelkman Rooda, Oscar H. J., Spanke, Jochen K., Alva, Parimala, van Dongen, Marijn N., Karapatis, Athanasios, Tolner, Else A., Strydis, Christos, Davey, Neil, Winkelman, Beerend H. J., Negrello, Mario, Serdijn, Wouter A., Steuber, Volker, van den Maagdenberg, Arn M. J. M., De Zeeuw, Chris I., Hoebeek, Freek E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008217/
https://ncbi.nlm.nih.gov/pubmed/25762286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24399
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