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Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4(+) T Cells In Vitro

The latent HIV-1 reservoir primarily resides in resting CD4(+) T cells which are a heterogeneous population composed of both naive (T(N)) and memory cells. In HIV-1-infected individuals, viral DNA has been detected in both naive and memory CD4(+) T cell subsets although the frequency of HIV-1 DNA is...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zerbato, Jennifer M., Serrao, Erik, Lenzi, Gina, Kim, Baek, Ambrose, Zandrea, Watkins, Simon C., Engelman, Alan N., Sluis-Cremer, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008097/
https://ncbi.nlm.nih.gov/pubmed/27356901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00553-16
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