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Immunization with Attenuated Equine Herpesvirus 1 Strain KyA Induces Innate Immune Responses That Protect Mice from Lethal Challenge

Equine herpesvirus 1 (EHV-1) is a major pathogen affecting equines worldwide. The virus causes respiratory disease, abortion, and, in some cases, neurological disease. EHV-1 strain KyA is attenuated in the mouse and equine, whereas wild-type strain RacL11 induces severe inflammation of the lung, cau...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kim, Seong K., Shakya, Akhalesh K., O'Callaghan, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008086/
https://ncbi.nlm.nih.gov/pubmed/27356904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00986-16
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