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Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types

The herpes simplex virus 1 (HSV-1) ICP0 protein is an E3 ubiquitin ligase that promotes the degradation of several host cell proteins. Most studies have found that ICP0 promotes the loss of IFI16 in infected cells, but one study reported that ICP0 was not necessary or sufficient for loss of IFI16 in...

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Bibliographic Details
Published in:J Virol
Main Authors: Orzalli, Megan H., Broekema, Nicole M., Knipe, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008076/
https://ncbi.nlm.nih.gov/pubmed/27412599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00939-16
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