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Tumor-penetrating peptide fused EGFR single-domain antibody enhances cancer drug penetration into 3D multicellular spheroids and facilitates effective gastric cancer therapy

Human tumors, including gastric cancer, frequently express high levels of epidermal growth factor receptors (EGFRs), which are associated with a poor prognosis. Targeted delivery of anticancer drugs to cancerous tissues shows potential in sparing unaffected tissues. However, it has been a major chal...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Control Release
मुख्य लेखकों: Sha, Huizi, Zou, Zhengyun, Xin, Kai, Bian, Xinyu, Cai, Xueting, Lu, Wuguang, Chen, Jiao, Chen, Gang, Huang, Leaf, Blair, Andrew M., Cao, Peng, Liu, Baorui
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008032/
https://ncbi.nlm.nih.gov/pubmed/25553823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.12.039
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