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Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury

Axon injury in the peripheral nervous system (PNS) induces a regeneration-associated gene (RAG) response. Atf3 (activating transcription factor 3) is such a RAG and ATF3's transcriptional activity might induce ‘effector’ RAGs (e.g. small proline rich protein 1a (Sprr1a), Galanin (Gal), growth-a...

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Publicat a:Open Biol
Autors principals: Gey, Manuel, Wanner, Renate, Schilling, Corinna, Pedro, Maria T., Sinske, Daniela, Knöll, Bernd
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008009/
https://ncbi.nlm.nih.gov/pubmed/27581653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160091
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