Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma

Patients with pancreatic ductal adenocarcinoma (PDAC) face a clinically intractable disease with poor survival rates, attributed to exceptionally high levels of metastasis. Epithelial-to-mesenchymal transition (EMT) is pronounced at inflammatory foci within the tumor; however, the immunological mech...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Penny, Hweixian Leong, Sieow, Je Lin, Adriani, Giulia, Yeap, Wei Hseun, See Chi Ee, Peter, San Luis, Boris, Lee, Bernett, Lee, Terence, Mak, Shi Ya, Ho, Ying Swan, Lam, Kong Peng, Ong, Choon Kiat, Huang, Ruby Y. J., Ginhoux, Florent, Rotzschke, Olaf, Kamm, Roger D., Wong, Siew Cheng
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007961/
https://ncbi.nlm.nih.gov/pubmed/27622062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1191731
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