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Mechanotransduction and cartilage integrity

Osteoarthritis (OA) is characterized by the breakdown of articular cartilage that is mediated in part by increased production of matrix metalloproteinases (MMPs) and aggrecanases (ADAMTS), enzymes that degrade components of the cartilage extracellular matrix. Efforts to design synthetic inhibitors o...

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Detalles Bibliográficos
Publicado en:Ann N Y Acad Sci
Main Authors: Leong, Daniel J., Hardin, John A., Cobelli, Neil J., Sun, Hui B.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007871/
https://ncbi.nlm.nih.gov/pubmed/22172037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06301.x
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