The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells

BACKGROUND: In mouse ES cells, the function of Sox2 is essential for the maintenance of pluripotency. Since the Sox-family of transcription factors are well conserved in the animal kingdom, addressing the evolutionary origin of Sox2 function in pluripotent stem cells is intriguing from the perspecti...

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書目詳細資料
發表在:BMC Evol Biol
Main Authors: Niwa, Hitoshi, Nakamura, Akira, Urata, Makoto, Shirae-Kurabayashi, Maki, Kuraku, Shigehiro, Russell, Steven, Ohtsuka, Satoshi
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007870/
https://ncbi.nlm.nih.gov/pubmed/27582319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-016-0755-4
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