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Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution

The normal distribution of nuclear envelope transmembrane proteins (NETs) is disrupted in several human diseases. NETs are synthesized on the endoplasmic reticulum and then transported from the outer nuclear membrane (ONM) to the inner nuclear membrane (INM). Quantitative determination of the distri...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mudumbi, Krishna C, Schirmer, Eric C, Yang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007294/
https://ncbi.nlm.nih.gov/pubmed/27558844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12562
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