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The mammalian dynein/dynactin complex is a strong opponent to kinesin in a tug-of-war competition
Kinesin and dynein motors transport intracellular cargos bidirectionally by pulling them in opposite directions along microtubules, through a process frequently described as a ‘tug of war’. While kinesin produces a 6 pN force, mammalian dynein was found to be a surprisingly weak motor (0.5–1.5 pN) i...
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| Udgivet i: | Nat Cell Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007201/ https://ncbi.nlm.nih.gov/pubmed/27454819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3393 |
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