PagP Crystallized from SDS/Cosolvent Reveals the Route for Phospholipid Access to the Hydrocarbon Ruler

Enzymatic reactions involving bilayer lipids occur in an environment with strict physical and topological constraints. The integral membrane enzyme PagP transfers a palmitoyl group from a phospholipid to lipid A in order to assist Escherichia coli in evading host immune defenses during infection. Pa...

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Gepubliceerd in:Structure
Hoofdauteurs: Cuesta-Seijo, Jose Antonio, Neale, Chris, Khan, M. Adil, Moktar, Joel, Tran, Christopher D., Bishop, Russell E., Pomès, Régis, Privé, Gilbert G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007126/
https://ncbi.nlm.nih.gov/pubmed/20826347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.014
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