Structural modifications of outer membrane vesicles to refine them as vaccine delivery vehicles

In an effort to devise a safer and more effective vaccine delivery system, outer membrane vesicles (OMVs) were engineered to have properties of intrinsically low endotoxicity sufficient for the delivery of foreign antigens. Our strategy involved mutational inactivation of the MsbB (LpxM) lipid A acy...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Kim, Sang-Hyun, Kim, Keun-Su, Lee, Sang-Rae, Kim, Ekyune, Kim, Myeong-Su, Lee, Eun-Young, Gho, Yong Song, Kim, Jung-Woo, Bishop, Russell E., Chang, Kyu-Tae
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007125/
https://ncbi.nlm.nih.gov/pubmed/19695218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.08.001
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