Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori

In Bombyx mori (B. mori), Fem piRNA originates from the W chromosome and is responsible for femaleness. The Fem piRNA-PIWI complex targets and cleaves mRNAs transcribed from the Masc gene. Masc encodes a novel CCCH type zinc-finger protein and is required for male-specific splicing of B. mori double...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Autores principales: Sakai, Hiroki, Sumitani, Megumi, Chikami, Yasuhiko, Yahata, Kensuke, Uchino, Keiro, Kiuchi, Takashi, Katsuma, Susumu, Aoki, Fugaku, Sezutsu, Hideki, Suzuki, Masataka G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007099/
https://ncbi.nlm.nih.gov/pubmed/27579676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006203
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