The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activity

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of skeletal muscle origin in children and adolescents. Among RMS subtypes, alveolar rhabdomyosarcoma (ARMS), which is characterized by the presence of the PAX3-FOXO1A or PAX7-FOXO1A chimeric oncogenic transcription factor, is associated w...

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Pubblicato in:Mol Biol Cell
Autori principali: Thuault, Sylvie, Comunale, Franck, Hasna, Jessy, Fortier, Mathieu, Planchon, Damien, Elarouci, Nabila, De Reynies, Aurélien, Bodin, Stéphane, Blangy, Anne, Gauthier-Rouvière, Cécile
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007086/
https://ncbi.nlm.nih.gov/pubmed/27413008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-01-0041
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