Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

Unlike for other retroviruses, only a few host cell factors that aid the replication of foamy viruses (FVs) via interaction with viral structural components are known. Using a yeast-two-hybrid (Y2H) screen with prototype FV (PFV) Gag protein as bait we identified human polo-like kinase 2 (hPLK2), a...

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Publicado en:PLoS Pathog
Main Authors: Zurnic, Irena, Hütter, Sylvia, Rzeha, Ute, Stanke, Nicole, Reh, Juliane, Müllers, Erik, Hamann, Martin V., Kern, Tobias, Gerresheim, Gesche K., Lindel, Fabian, Serrao, Erik, Lesbats, Paul, Engelman, Alan N., Cherepanov, Peter, Lindemann, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006980/
https://ncbi.nlm.nih.gov/pubmed/27579920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005860
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