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Prototype Foamy Virus Protease Activity Is Essential for Intraparticle Reverse Transcription Initiation but Not Absolutely Required for Uncoating upon Host Cell Entry

Foamy viruses (FVs) are unique among retroviruses in performing genome reverse transcription (RTr) late in replication, resulting in an infectious DNA genome, and also in their unusual Pol biosynthesis and encapsidation strategy. In addition, FVs display only very limited Gag and Pol processing by t...

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Detalhes bibliográficos
Main Authors: Hütter, Sylvia, Müllers, Erik, Stanke, Nicole, Reh, Juliane, Lindemann, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592149/
https://ncbi.nlm.nih.gov/pubmed/23283957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02323-12
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