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Ewing Sarcoma With ERG Gene Rearrangements: A Molecular Study Focusing on the Prevalence of FUS-ERG and Common Pitfalls in Detecting EWSR1-ERG Fusions by FISH

The genetics of Ewing sarcoma (ES) are characterized by a canonical fusion involving EWSR1 gene and a member of the ETS family of transcription factors, such as FLI1 and ERG. In fact, ERG gene rearrangements represent the second most common molecular alteration, with EWSR1-ERG being identified in 5–...

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Detalles Bibliográficos
Publicado en:Genes Chromosomes Cancer
Autores principales: Chen, Sonja, Deniz, Kemal, Sung, Yun-Shao, Zhang, Lei, Dry, Sarah, Antonescu, Cristina R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006947/
https://ncbi.nlm.nih.gov/pubmed/26690869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22336
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