Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium.
The toxin N-methyl-1,2,3,6-tetrahydropyridine produces a model of neural degeneration very similar to idiopathic Parkinson disease. To understand the cellular mechanisms that modulate susceptibility to its active metabolite N-methyl-4-phenylpyridinium (MPP+), we have transfected a cDNA expression li...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9074 |
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