Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves

Individuals with bicuspid aortic valves (BAV) are at a higher risk of developing thoracic aortic aneurysms (TAA) than patients with trileaflet aortic valves (TAV). The aneurysms associated with BAV most commonly involve the ascending aorta and spare the descending aorta. Smooth muscle cells (SMCs) i...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Jiao, Jiao, Xiong, Wei, Wang, Lunchang, Yang, Jiong, Qiu, Ping, Hirai, Hiroyuki, Shao, Lina, Milewicz, Dianna, Chen, Y. Eugene, Yang, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006642/
https://ncbi.nlm.nih.gov/pubmed/27394642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.045
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