Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach

BACKGROUND: Epigenetic silencing mediated by CpG island methylation is a common feature of many cancers. Characterizing aberrant DNA methylation changes associated with prostate carcinogenesis could potentially identify a tumour-specific methylation pattern, facilitating the early diagnosis of prost...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Gurioli, Giorgia, Salvi, Samanta, Martignano, Filippo, Foca, Flavia, Gunelli, Roberta, Costantini, Matteo, Cicchetti, Giacomo, De Giorgi, Ugo, Sbarba, Persio Dello, Calistri, Daniele, Casadio, Valentina
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006561/
https://ncbi.nlm.nih.gov/pubmed/27576364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1014-6
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