Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

Paediatric brain tumours arising in the thalamus present significant diagnostic and therapeutic challenges to physicians due to their sensitive midline location. As such, genetic analysis for biomarkers to aid in the diagnosis, prognosis and treatment of these tumours is needed. Here, we identified...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Ryall, Scott, Krishnatry, Rahul, Arnoldo, Anthony, Buczkowicz, Pawel, Mistry, Matthew, Siddaway, Robert, Ling, Cino, Pajovic, Sanja, Yu, Man, Rubin, Joshua B., Hukin, Juliette, Steinbok, Paul, Bartels, Ute, Bouffet, Eric, Tabori, Uri, Hawkins, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006436/
https://ncbi.nlm.nih.gov/pubmed/27577993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0353-0
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