Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

Paediatric brain tumours arising in the thalamus present significant diagnostic and therapeutic challenges to physicians due to their sensitive midline location. As such, genetic analysis for biomarkers to aid in the diagnosis, prognosis and treatment of these tumours is needed. Here, we identified...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Ryall, Scott, Krishnatry, Rahul, Arnoldo, Anthony, Buczkowicz, Pawel, Mistry, Matthew, Siddaway, Robert, Ling, Cino, Pajovic, Sanja, Yu, Man, Rubin, Joshua B., Hukin, Juliette, Steinbok, Paul, Bartels, Ute, Bouffet, Eric, Tabori, Uri, Hawkins, Cynthia
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006436/
https://ncbi.nlm.nih.gov/pubmed/27577993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0353-0
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