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Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements

BACKGROUND: Diversity-generating retroelements (DGRs) provide organisms with a unique means for adaptation to a dynamic environment through massive protein sequence variation. The potential scope of this variation exceeds that of the vertebrate adaptive immune system. DGRs were known to exist only i...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Main Authors: Handa, Sumit, Paul, Blair G., Miller, Jeffery F., Valentine, David L., Ghosh, Partho
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006420/
https://ncbi.nlm.nih.gov/pubmed/27578274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0064-6
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