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Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children

Background. The targets and mechanisms of human immunity to malaria are poorly understood, which poses a major barrier to malaria vaccine development. Antibodies play a key role in human immunity and may act by inhibiting receptor-binding functions of key merozoite invasion ligands. Antibodies to th...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Irani, Vashti, Ramsland, Paul A., Guy, Andrew J., Siba, Peter M., Mueller, Ivo, Richards, Jack S., Beeson, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006303/
https://ncbi.nlm.nih.gov/pubmed/26136391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ525
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